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Emerging Smart Nanobiosensing Technologies for Personalized Medicine


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Date:  Thu, April 12, 2018
Time:  2:00pm
Location:  Holmes 389
Speaker:  Rahim Esfandyarpour, Faculty Candidate

Abstract:

Despite significant advancements in all three fields of engineering and nanotechnology, medicine and biology, and artificial intelligence computing, the lack of bridge among them has hindered the effectiveness of the way in which medicine is practiced as well as how patients are monitored, diagnosed and treated. Aiming to address these challenges, our multidisciplinary research focuses on using innovative approaches to develop next-generation, novel, innovative, state-of-the-art, cost-effective, high-throughput, easy to use and accurate nanotechnology-based platforms to advance the translation of biomedical research into advanced diagnostics and treatments in the field of precision medicine. Therefore, we have developed a wide variety of platforms, which includes: a) ultra-low-cost, rapid, high-throughput and miniaturized lab-on-a-chip (LOC) platforms for the isolation and characterization of rare cells and molecules from a heterogeneous population, as critical in the diagnosis of common lethal diseases such as malaria, tuberculosis, HIV, and cancer, b) versatile, ultra-sensitive, matrix-independent, and high-throughput impedance-based nano electronic arrays integrated with microfluidics technology for reliably performing real-time and label-free affinity-based bio sensing of target cancer related biomarkers, c) flexible wearable and portable sensing platforms along with the artificial intelligence based computing systems for health monitoring, d) and precise, sensitive, robost, and high-throughput BioMEMS-based molecular screening technology for genomic analysis, perturbation, and manipulation of single tumor cells.

Bio:

Dr. RahimĀ  Esfandyarpour received his M.Sc. and Ph.D. in Electrical Engineering from Stanford University, in 2010 and 2014 respectively. Currently, as an Engineering Research Associate at Stanford Genome Technology Center, Stanford Biochemistry Department and Stanford Medical School, he is leading a group of scientists and engineers working on several cutting-edge research projects. Dr. Esfandyarpour's interdisciplinary research focuses on translational science by applying innovative engineering concepts to address major challenges in modern life science and medicine with the three main aims of prevention, early diagnosis, and effective treatments of the diseases. Dr. Esfandyarpour's research interests cover a broad swatch of engineering disciplines that are the interface of nano(bio)technology, device physics, nanoelectronics and nano(micro) fabrication, smart sensing and wearable technologies, artificial intelligence computing, and wireless and cell phone-based communication systems. Dr. Esfandyarpour's research works have been highlighted by several news agencies, such as Nature News, New Scientist, Yahoo News, BBC World Service, StanfordMedNews, Popular Science, Gizmodo, Europa Press, Science Daily, AzoNano, Engineer Online, Healthcare IT News, Tech Times, Phys.org, Laboratory news, and several others.


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