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Harnessing Ultrasound Waves to Develop Next-Generation Diagnostic and Therapeutic Methods


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Date:  Tue, February 27, 2024
Time:  3:30pm - 5:00pm
Location:  Holmes Hall 244
Speaker:  Dr. Murad Hossain, Assistant Professor


Abstract

Ultrasound is a low-cost, non-ionizing, and portable diagnostic imaging modality and is easily translatable from laboratory-based feasibility studies to clinics. In addition to diagnosis, ultrasound can be applied for therapy such as focused ultrasound (FUS)-induced thermal ablation of cancer. In this talk, I will discuss how these advantages of Ultrasound can be harnessed by modifying beam and pulse sequences for diagnostic and therapeutic applications. We will discuss two different ultrasound-based methods: Viscoelastic Response and single transducer harmonic motion imaging and their applications on kidney dysfunction, breast cancer, and FUS-induced thermal ablation of cancer. Finally, I will end the talk with a discussion of different experimental and computational projects available to the students in the lab.

Biography

LinkedIn | Google Scholar: Dr. Murad Hossain is an Assistant Professor in the Department of Electrical and Computer Engineering at the University of Hawaiʻi at Mānoa. He was an Associate Research Scientist and Post-Doctoral Research Scientist in Prof. Elisa E. Konofagou’s Lab at Columbia University, New York. He received a B.Sc. degree in Electrical and Electronic Engineering from the Islamic University of Technology, Bangladesh in 2009, M.Sc. degree in Electrical Engineering from George Mason University, Fairfax, VA, USA in 2014, and Ph.D. degree in Biomedical Engineering from the Joint Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC, USA, and North Carolina State University, Raleigh, NC, in 2019. During his Ph.D., he developed Viscoelastic Response (VisR) ultrasound to interrogate viscoelastic and anisotropic properties of tissue and applied VisR-derived viscoelastic and anisotropic properties to detect kidney dysfunction in renal transplant patients. At Columbia University, Dr. Hossain developed single transducer-harmonic motion imaging (ST-HMI) to assess frequency-specific mechanical properties of tissue and applied ST-HMI for diagnosis and chemotherapy monitoring of breast cancer patients. In addition, he also worked on focused ultrasound-induced thermal ablation of breast tumors and neuromodulation. He was awarded the IEEE IUS conference travel, UNC BME department travel and workshop, NCSU graduate merit, and GMU Chairman awards.

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