Research Activities

Research Interests:

·        Advanced computing and communication;

·        Bio-medical engineering; intelligent system;

·        3D imaging, modeling and visualization;

·        Resource management by planning and scheduling;

·        Tele-health systems and remote telemedicine. 

·        East-West medicine and technology

Awards and Recognitions

·         Highlighted in the State of Hawaii Technology Innovation Report, 2001 Millennium Edition.

·         For its achievements in healthcare technology, Dr. Yun, the Director of LIPS, was featured by the Honolulu Advertiser (3/01) and Wired News (11/99) as "Mr. Telemedicine".

Grants

·        Title: Positron Emission Tomography Guided Prostate Biopsy, $205,000, SBIR/STTR grant, in collaboration with Queens Medical Center, Start date: 9/1/04; End date: 6/30/06; sponsoring agency: National Institute of Health, National Cancer Institute.

·        $50,000 extension of Electric and Hybrid Vehicle (EHV) National Data Center (NDC), to 12/03.

·        $100,000 extension of Simulation and Validation in Bio-Photonics, to 6/02.

·        Title: Enhancements to Web System Support for Remote Monitoring and Diabetes Self-Management, Dollar amount: $126,000 Start date: 9/1/00; End date: 8/31/01; No cost extension to 8/31/02; Sponsoring agency: HMSA Foundation

·        Title: Telemedicine on the Internet – Remote Monitoring and Screening or the Ohana Health Project; Dollar amount: $202,500, Start date: 9/1/99; End date: 8/31/00; Sponsoring agency: Department of Defense via Georgetown University Medical Center;

·        Title: Dollar amount: $1,746,725, Start date: 5/1/95; End date: 12/31/00; Sponsoring agency: Defense Advanced Research Projects Agency (DARPA) via Hawaii's High Technology Development Corp.;

·        Title: Simulation and Validation in Bio-Photonics; Dollar amount: $570,000, Start date: 4/1/97; End date: 12/31/00; Sponsoring agency: Hamamatsu Photonics K. K. of Japan;

·        Title: Center for East-West Medicine Projects, international support for research, Ministry of Education, Taiwan, ROC, July 1996-2000, $237,000.

·        Title: ACTS and Supercomputing in Remote, Cooperative MedicalTriage Support and Radiation Treatment Planning, also known as Project MISSION, $2,800,000, Start date: 9/1/94; End date: 12/31/99; Sponsoring agency: DARPA Networks Program.

Patents

·        David Y. Y. Yun and Tianyu Lu, Inventors. Triangular Mesh Generation for Surfaces of 3D Objects, filed in the USA as a Provisional Patent Application by OTTED of the University of Hawai'i, November 2000, and assigned to D. Y. Y. Yun by OTTED in September 2001.

Faculty Collaborators:

·        Healani Chang, Assistant Professor PBRC, on topics of Ohana Health Online and Chronic Disease Management (since 2004).

·        Joshua I. Santos, UH Honor student, received the "Best Poster" award at National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) Undergraduate Research Conference at the University of Maryland, Baltimore County (UMBC) on August 12, 2004.

·        Dr. Joseph W. Humphry, Clinical Assistant Professor, School of Medicine (since 1999), research collaboration and providing support on two projects: Ohana Health and the HMSA Foundation work, involving telemedicine efforts with diabetes patients.

·        Prof. Vassilis L. Syrmos, Electrical Engineering Department, research collaboration and providing support as Co-I (since 1995) on two projects: simulation and modeling of electric and hybrid electric vehicles for the EHV DNC Project and finite element solution of inverse problems for the Bio-Photonics Project.

·        Prof. Hong-Mei Chen, Information Technology Management Department, College of Business, research collaboration and providing support as Co-I (1995-2001) on two projects: database applications for electric vehicle performance data for the EHV NDC Project and distributed data sharing and graphic visualization for Project MISSION.

·        Prof. Milan Sonka, Electrical Engineering, University of Iowa, visiting faculty for collaborative teaching of EE491f – Image Processing (using his text book) and collaborative research on computer image processing and graphics (1/6—2/11/00).

·        Prof. Mehrdad G. Nejhad, Mechanical Engineering Department, research collaboration and providing support as Co-I (1996—1999) on composite material and crash simulation of electric vehicles for the EHV NDC Project.

·        Dr. Borr Yan Liaw, Hawaii Natural Energy Institute, research collaboration and providing support as manager for the EHV NDC project (1994—1999), with research activities involving battery testing operations

·        Prof. Ming Pi Mi, emeritus, Department of Molecular Genetics, School of Medicine (1997-2001), research collaboration and providing support on the Bio-Photonics project, with emphasis on statistical data analysis.

Post-Doctoral Fellows (Trained recently):

·        Dr. Hai Wei from Beijing Polytechnic University, People's Republic of China, post-doc for research on imaging processing in bio-medical systems (Since February 2001).

·        Dr. C. H. Liao from People's Republic of China, post-doc on laser characterization and measurement analysis for the Bio-Photonics Project (January 2001—March 15, 2001)

·        Prof. Milan Sonka, Electrical Engineering, University of Iowa, visiting faculty for collaborative teaching of EE491f – Image Processing (using his text book) and collaborative research on computer image processing and graphics (1/6—2/11/00).

·        Dr. Junhai Wen from People's Republic of China, post-doc on helmet device and hemisphere simulation and validation for the Bio-Photonics Project (January 2000—December 2000).

·        Dr. Jun Ge from Tsin Hua University, People's Republic of China, post-doc for research on simulation and validation in bio-photonics (July 1998 – January 2000).

·        Dr. Guenter Randolf from Austria, post-doc for research on battery simulation and life extension by use of supercapacitors (April 1998 – July 1999).

·        Dr. Yaoyu Wang from People's Republic of China, post-doc on battery performance monitoring and analysis for the EHV NDC Project (January 1999 – September 1999).

·        Dr. Mangesh Tamhankar from India, post-doc for the development of on-line reporting systems for technical/economic information of electric vehicles and research on data mining from electric vehicle performance data (August 1997 – July 1999)

·        Dr. Susan Spiessberger from Austria, post-doc on photon physics and measurement verification for the Bio-Photonics Project (Dec.1998 – July 1999).

Students (completed degrees recently):

·        Tianyu Lu (1996-2000), Advisor and Chairman of Ph.D. dissertation committee, passed defense on June 8, 2000, Ph.D. degree completed in August 2000, Title: Triangular Mesh Generation for Surfaces of 3D Objects.

·        Kevin Chao-wen Chen (1995-1999), Advisor and Chairman of Ph.D. dissertation committee, Ph.D. degree completed in August 1999, Title: Algorithms for Maximal Common Subgraph Problem Using Resource Planning.

·        Sixiang Nie (1999-2003), Advisor and Chairman of MS thesis committee, "Solving Photon Diffusion Equation by Lanczos Algorithm for Rectangular and Hemisphere Phantoms".

·         Dan Shnidman (2001-2003), Advisor and Chairman of MS thesis committee, "Solving Two-Dimensional and Three-dimensional Packing Problems using Constraint Resource Planning"

·        Zisheng Le (1998-2000), Advisor and Chairman of MS thesis committee, passed defense on May 30, 2000, M.S. degree completed in June 2000, Title: Geometric Compression.

·        Ashutosh Deepak Gore (1998-2000), MS thesis committee member, degree completed in February 2000, Title: Simulation and performance analysis of optical WDM networks with limited wavelength conversion.

·        Zong Ling (1994-1998), Advisor and Chairman of Ph.D. dissertation committee, Ph.D. degree completed in May 1998, Title: Subgraph Isomorphism

·        Javed I. Khan (1993-1997) Advisor and Chairman of Ph.D. dissertation committee, Ph.D. degree completed in August 1997, Title: Content-based Image Retrieval.

·        Zisheng Le (1998-2000), Advisor and Chairman of MS thesis committee, passed defense on May 30, 2000, Title: Geometric Compression.

·        Julie Yu, (1995-1998), Advisor and Chairman of MS thesis committee, degree completed in May 1998, Title: EHV National Data Center Website and Database.

Publications and Reports (selected and key):

Articles in refereed archival journals:

·        A Numerical Algorithm for the Diffusion Equation Using 3D FEM and the Arnoldi Method (with Q. Su and V. Syrmos), Circuits, Systems and Signal Processing, Vol. 18, pp. 291-314, July 1999.

·        Knowledge Discovery for Protein Tertiary Substructures, (with C. W. Chen), Lecture Notes in Artificial Intelligence series, Springer-Verlag, 2000.

·        Intelligent Resource Management through the Constrained Resource Planning Engine, Future Directions for Intelligent Systems and Information Sciences, Chapter 18, N. Kasabov, ed., pp. 373-386, Springer-Verlag, 2000.

·        Inverse Solutions for the diffusion equation, (with J. Yin and V. L. Syrmos), IEEE Trans. on Medical Imaging, June 2000.

·        Solving a Family of Graph Matching Problems using the Constrained Resource Planning (CRP) Paradigm, Congressus Numerantium Vol. 142-147, 2000.

·        Discovering Process Models from Execution History by Graph Matching, (with C. W. Chen), Proc. Fourth International Conf. on Intelligent Data Engineering and Automated Learning (IDEAL2003), also in Lecture Notes in Computer Science, Springer Verlag.

Articles in refereed conference proceedings:

·        Compression Techniques in Tele-radiology, (with T. Lu and Z. Xiong), Proc. Applications of Digital Imaging Processing XXII Conf., 44^th SPIE Annual Meeting, Denver, July 1999.

·        The Multi-grid ADI Algorithm in Solving Diffusion Equation, (with J. Ge),44^th SPIE, Proc. Photonic Devices and Algorithms for Computing Conference, Denver, July 1999.

·        The Photon Diffusion Equation: Forward and Inverse Problems, (with V. Syrmos, J. Yin, and P. Misra), 1999 Proc. of the joint IEEE International Symposium on Control Applications & IEEE International Symp. on Computer Aided Control System Design, Kona, HI, Aug'99.

·        Knowledge Discovery for Protein Tertiary Substructures, (with C. W. Chen), Proc. 7th Symp. on Rough Sets, Fuzzy Sets, Data Mining, & Granular-Soft Computing, Japan, 11/99.

·        Intelligent Resource Management through the Constrained Resource Planning Engine, Proc. International Workshop on Future Directions for Intelligent Systems and Information Sciences, Dunedin, New Zealand, Nov. 1999.

·        Optimizing Triangular Mesh Generation from Range Images, (with T. Lu), Proc. SPIE Electronic Imaging, Conf. on 3D Image Capture and Applications III, Jan. 2000.

·        A comparison study between the FEM and ADI techniques for the solution to the diffusion equation, (with S. Nie, J. Ge, and V.L. Syrmos), SPIE, Proc. International Symposium on Biomedical Optics, San Jose, CA, Jan., 2000.

·        Visualization of Photon Propagation and Abnormality Detection, (with J. Ge and Z. Le), SPIE Photonics West, Proc. International Symposium on Biomedical Optics, Vol. 3917, Optical Biopsy III, pp. 204-21, Jan. 2000

·        Simulation Comparisons of Diffusion Equation, (with J. Ge, S. Nie and V. L. Syrmos), Proc. Intrn'l Symp. on Biomedical Optics, Vol. 3917, pp. 212-218, San Jose, CA, Jan. 2000.

·        Optimizing Triangular Mesh Generation from Range Images, (with T. Lu), Proc. SPIE, Volume 3958, Three-Dimensional Image Capture and Applications III, pp.161-169 and IST 12th Annual International Symposium, Science & Technology, pp. 23-28.

·        Piecewise Linear Image Compression Using Surface Triangulation and Geometric Compression (with T. Lu and Z. Le), IEEE Data Compression Conference (DCC'00), Snowbird, UT, Mar. 2000.

·        Progressive Registration of Range Images Based On Surface Triangulation, (with H. Ma and T. Lu), SPIE International Symposium on Optical Science and Technology, Conference on Applications of Digital Image Processing XXIII, San Diego, CA, July 2000.

·        The Use of the Internet for Home Glucose Monitoring in a Lower Income Asian/Pacific Islander Community, (with J. W. Humphry), American Diabetes Association International Symposium on Computer and Diabetes Care, Sept. 2000. Rochester, MN.

·        Inverse Solutions for the diffusion equation, (with J. Yin and V. L. Syrmos), IEEE Conf.  on Control Applications and Symp. on Computer-Aided System Design, Anch., AL, Sept. 2000.

·        System Identification using Nonlinear Filtering Methods with Applications to Medical Imaging, (with J. Yin and V. Syrmos), Proc. 39th IEEE Conf. on Decision and Control, Australia, Oct. 2000.

·        3D Image Reconstruction for Optical Time-Resolved Data, (with J. Wen and S. Nie), Proc. 15th International Congress on Computer Assisted Radiology and Surgery, Berlin, June 27-30, 2001.

·        Illumination-Invariant Image Indexing Using Directional Gradient Angular Histogram, (with H. Wei), Proceeding of the IASTED International Conference on Computer Graphics and Imaging, pp. 124-129, Honolulu, Hawaii, August 2001

·        Multi-agent parallelization of 3D surface approximation with quality assurance and space efficiency, (with H. Wei, T. Lu), Proc. the IASTED International Conference on Parallel and Distributed Computing and Systems, pp. 130-135, Honolulu, Hawaii, Aug. 2001.

·        Naturally Convergent and Optimal 3D Surface Mesh Generation, (with H. Wei), Proceedings of SPIE on Visualization and Data Analysis, Vol. 4665, pp. 22-31, San Jose, Jan. 2002

·        Achieving Computational Intelligence by Resource Optimization, (Invited Paper) Proc. 2002 World Congress on Computational Intelligence, International Joint Conference on Neural Networks, Honolulu, May 2002.

·        Joint Image Compression and Indexing Technique using Wavelet Transforms, (with H. Wei), Proc. Conf. On Vision Geometry XI, SPIE Vol., 4794, Seattle, July, 2002.

·        Discovering Process Models from Execution History by Graph Matching, (with C. W. Chen), Proc. Fourth International Conf. on Intelligent Data Engineering and Automated Learning (IDEAL2003).

Invited lectures, symposia, workshop and seminar presentations (recent):

·        Tele-Radiology Exemplifying Tele-Medicine, University Connections Invited Lecture, March 6, 2000.

·        Solving a Family of Graph Matching Problems using the Constrained Resource Planning (CRP) Paradigm, Florida Atlantic University, Ft. Lauderdale, FL: Invited Plenary Speaker, 31st Southeastern International Conference on Combinatorics, Graph Theory and Computing, March, 2000.

·        Applications of Hawaii-Grown Technologies in BioPhotonics 3D Imaging and Telemedicine for International Collaboration,

·        Banquet Speaker, Japan-U.S. Science, Technology & Space Applications Symposium, Hilo, HI, November, 2000.

·        Telemedicine and Technology, Keynote Address (1 hour), 2001 Pacific Rim Conference, American Academy of Medical Administrators and American College of Healthcare Executives, August 7-8, 2001.

·        "HI-Tech" = Hawaii's own Technology: Virtual-X (X = clinic, experiments, laboratory, presence and reality), presentation and demonstration to UH Deans Council, Dec. 4, 2001.

·        ICE (Institute for Computed Experiments), invited seminar speaker, UH Civil Engineering graduate seminars, April 2002.

·        Achieving Computational Intelligence by Resource Optimization, (Invited talk, 40-min) Proc. 2002 World Congress on Computational Intelligence, International Joint Conference on Neural Networks, Honolulu, May 2002.

·        3D Image Visualization with Applications in BioMedical Engineering, Georgetown University Medical Center, Washington DC, November 22, 2002.

·        "Computational Biophotonics, Image Reconstruction, and Protein 3D Structure Matching", (invited instructor), Workshop on Biophotonics, Jan. 13 – 16, 2003, East West Center.

·        "Computational Bio-Photonics in 3D – Challenges, Results and Opportunities in Computing, Visualizing, Communicating, …", (Invited luncheon speaker, to Honolulu high-tech business leaders), University Connections program of UH, Friday March 14, 2003.